Guusje Delen

PhD candidate
Employed since: September 2016
Phone: +31610213294
Room: David de Wied 4th floor study area



The pressing need for a more sustainable society has sparked intensive efforts in search for novel materials with controlled structure, porosity and functionalities. Such porous materials may combine high catalytic activity and selectivity with a long-term stability in the conversion of both renewable (e.g. biomass) and non-renewable feedstock when producing future transportation fuels, chemicals and pharmaceutical intermediates. The rational design and optimization of the catalytic properties of these materials is one of the keys for the transition from a fossil fuels based society to a sustainable society.

Unfortunately, useful porous catalytic solids are still largely discovered through a combination of trial-and-error, serendipity and high-throughput testing, mainly because not so much is known about the molecular details of their formation and working. Such detailed knowledge, however, is needed to tailor these porous solids towards optimal functioning.

The goal of my research is to obtain new fundamental insights in the formation principles and catalytic functioning of crystalline porous materials, namely metal organic frameworks (MOFs).

Nano-sized sheets of porous materials are constructed as model systems  amenable to nano-spectroscopic research.  To achieve this, Au substrates are functionalized to form self-assembled monolayers (SAMs) able to orient the growth of MOFs being grown by liquid phase epitaxy (LPE), or layer-by-layer growth (LBL). The effect of the variation of synthesis parameters, such as temperature, precursor solution dilution, growth time, etc., are studied.[1,2]

Novel analytical tools, such as scanning probe (SP) methods together with Raman and X-ray spectroscopy,  in combination with a specially designed high-pressure/high-temperature in-situ atomic force microscopy (AFM) cell allow for realistic measurement conditions. The novel tools and models will be used to study the intricate chemistry of synthesis, self-assembly and catalysis.

The newly developed SP-based tools are ideally suited for characterizing oxygenated molecules, which can for example be found in biomass conversion processes, as well as organic and inorganic building blocks building up the MOF materials. As a consequence, biomass conversion processes can be explored to evaluate the potential of the newly developed approach combining high pressure/temperature AFM for in-situ studies.

[1] O. Shekhah et al., Angew. Chem. Int. Ed., 48, 5038-5041, 2009
[2] Z. Gu, et al., Micropor. Mesopor. Mater., 211, 82-87, 2015
Universiteitsweg 99 | 3584 CG Utrecht | The Netherlands | Phone: +31 (0)30 253 7400



Bachelor ‘Chemistry’ at University of Birmingham

Bachelor ‘Scheikunde’ at Utrecht University

Master ‘Nanomaterials: Chemistry and Physics’ at Utrecht University

Previous work experience:

Teaching assistant at Utrecht University


Mandemaker, L D B; Rivera-Torrente, M; Delen, G; Hofmann, J P; Lorenz, M; Belianinov, A; Weckhuysen, B M

Nanoweb Surface-Mounted Metal–Organic Framework Films with Tunable Amounts of Acid Sites as Tailored Catalysts Journal Article

Chemistry - A European Journal, 2019, (cited By 0).

Links | BibTeX

Amirilargani, M; Yokota, G N; Vermeij, G H; Merlet, R B; Delen, G; Mandemaker, L D B; Weckhuysen, B M; Winnubst, L; Nijmeijer, A; de Smet, L C P M; Sudhölter, E J R

Melamine-Based Microporous Organic Framework Thin Films on an Alumina Membrane for High-Flux Organic Solvent Nanofiltration Journal Article

ChemSusChem, 2019, (cited By 0).

Links | BibTeX

Delen, G; Ristanović, Z; Mandemaker, L D B; Weckhuysen, B M

Mechanistic Insights into Growth of Surface-Mounted Metal-Organic Framework Films Resolved by Infrared (Nano-) Spectroscopy Journal Article

Chemistry - A European Journal, 24 (1), pp. 187-195, 2018, (cited By 3).

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Mandemaker, L D B; Filez, M; Delen, G; Tan, H; Zhang, X; Lohse, D; Weckhuysen, B M

Time-Resolved in Situ Liquid-Phase Atomic Force Microscopy and Infrared Nanospectroscopy during the Formation of Metal-Organic Framework Thin Films Journal Article

Journal of Physical Chemistry Letters, 9 (8), pp. 1838-1844, 2018, (cited By 2).

Links | BibTeX

Brand, R P; Mandemaker, L D B; Delen, G; Rijnveld, N; Weckhuysen, B M

Behavior of a Metal Organic Framework Thin-Film at Elevated Temperature and Pressure as Studied with an Autoclave-Inserted Atomic Force Microscope Journal Article

ChemPhysChem, 19 (18), pp. 2397-2404, 2018, (cited By 0).

Links | BibTeX

Fu, D; Park, K; Delen, G; Attila, Ö; Meirer, F; Nowak, D; Park, S; Schmidt, J E; Weckhuysen, B M

Nanoscale infrared imaging of zeolites using photoinduced force microscopy Journal Article

Chemical Communications, 53 (97), pp. 13012-13014, 2017, (cited By 4).

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